Endocrine and metabolic mechanisms of embryo and fetal intrauterine growth retardation in dairy cows
نویسندگان
چکیده
Anatoliy NEZHDANOV, Sergey SHABUNIN, Vitaliy MIKHALEV, Nikolay KLIMOV, Anton CHERNITSKIY* Department of Reproduction and Mammary Gland Pathology, State Scientific Institution All-Russian Veterinary Research Institute of Pathology, Pharmacology, and Therapy of the Russian Academy of Agricultural Sciences, Voronezh, Russia Department of Pharmacology, State Scientific Institution All-Russian Veterinary Research Institute of Pathology, Pharmacology, and Therapy of the Russian Academy of Agricultural Sciences, Voronezh, Russia Department of Pathological Biochemistry and Pathological Physiology, State Scientific Institution All-Russian Veterinary Research Institute of Pathology, Pharmacology, and Therapy of the Russian Academy of Agricultural Sciences, Voronezh, Russia
منابع مشابه
The maternal, fetal and postnatal somatotrophic axes in intrauterine growth retardation.
Both the maternal and fetal somatotrophic axes are closely linked to fetal substrate supply. Nutritional insults at critical stages of fetal development may lead to permanent reprogramming of the relationships between these factors. The consequences of reprogramming during fetal life may be harmful to metabolic, endocrine and cardiovascular homoeostatic mechanisms in postnatal life. The exact m...
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Background: Metabolic profiles have been used in efforts to predict pre parturient problems and fertility, to diagnose metabolic diseases, and to assess nutritional status in dairy cows. These profiles may help to confirm the diagnosis of sub clinical diseases, to be aware of possible causes of infertility in the herds, or to monitor improvement in herd animals. OBJECTIVES: This study investiga...
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Intrauterine growth retardation (IUGR), defined as impaired growth and development of the mammalian embryo/fetus or its organs during pregnancy, is a major concern in domestic animal production. Fetal growth restriction reduces neonatal survival, has a permanent stunting effect on postnatal growth and the efficiency of feed/forage utilization in offspring, negatively affects whole body composit...
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Intrauterine growth retardation (IUGR) is a significant problem in livestock production. It adversely affects neonatal survival, postnatal growth performance, efficiency of feed utilization, tissue composition (including protein, fat and minerals), meat quality, long-term health of offspring, and adult onset of disease. Genetic, epigenetic and environmental factors (including nutrition), as wel...
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Fetal origin of adult diseases Epidemiological studies have shown a close correlation between intrauterine growth retardation (IUGR) and the onset of insulin resistance, non-insulin-dependent diabetes mellitus (NIDDM), hypertension, hyperlipidaemia, and cardiovascular diseases in adult life. To explain this association, the concept of re-programming has been introduced: intrauterine exposure to...
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